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Medivation, Inc. (Nasdaq: MDVN)
Global partnership with Astellas for MDV3100

Definitive agreement/closing: October 2009
Location: San Francisco, CA

Case Study    Press Release


CEO: David Hung
CFO: Patrick Machado

- Medivation is developing MDV3100, a novel, oral anti-androgen drug candidate for prostate cancer. After a successful Phase 2 trial, Medivation advanced MDV3100 into a pivotal Phase 3 trial in September 2009.

- Aquilo assisted Medivation throughout the MDV3100 partnering process, helping the company evaluate the financial, strategic and corporate governance aspects of potential partnerships.

- The economic aspects of the deal with Astellas include:

  • $110 million upfront payment
  • up to $335 million of development milestones
  • up to $320 million of commercial milestones 50/50 split of US profits
  • tiered double-digit royalties on ex-US sales